Player positions provided by the CFL and errors are known to exist
| Name | Position | Regular GP | # of Seasons (Years) | Also played for |
|---|---|---|---|---|
| Salata, Paul “Slats” | E | 21 | 2 (1951–1952) | OTT |
| Sam, P.K. | WR | 3 | 1 (2010) | TOR |
| Sampson, Oteman | QB | 19 | 2 (1999–2000) | OTT, TOR |
| Sanchez, Davis | DB | 16 | 1 (2003) | BC, EDM, MTL |
| Sanders, Jock | RB | 12 | 1 (2014) | BC, OTT, SSK |
| Sanderson, Norm | C | 7 | 2 (1945–1946) | |
| Sanford, Sulecio | WR | 18 | 1 (2004) | |
| Sankey, Ben | QB | 55 | 5 (2000–2002, 2007–2008) | BC, HAM |
| Sapunjis, Dave | SB, WR | 120 | 7 (1990–1996) | |
| Satele, Alvis | LB | 6 | 1 (1986) | BC |
| Savage, Ray | LB | 1 | 1 (1991) | SHR |
| Sawyer, Bob | HB | 10 | 2 (1959, 1961) | MTL |
| Sceviour, Ryan | OL | 1 | 1 (2018) | |
| Schaefer, Greg | OL | 18 | 1 (2004) | |
| Schlosser, Art | E | 27 | 2 (1960–1961) | TOR |
| Schumm, Herb | LB, T | 107 | 7 (1967–1973) | EDM |
| Schumm, Howie | T | 9 | 1 (1969) | EDM |
| Scolnik, Glenn | WR | 16 | 1 (1975) | HAM |
| Scott, Randy | LB | 3 | 1 (1980) | WPG |
| Scott, Sam | LB | 2 | 1 (2011) | HAM, WPG |
| Scott, Tom | SB | 14 | 1 (1984) | EDM, WPG |
| Scullion, Art | C, E | 61 | 4 (1957–1960) | HAM, TOR |
| Seaholm, J.T. | T | 15 | 1 (1958) | |
| Searight, Jerry | C | 7 | 2 (1945–1946) | CGYB, EDM, MTL |
| Senst, John | SE | 48 | 3 (1971–1973) | WPG |
| Seyferth, John “Fritz” Jr. | FB | 14 | 2 (1972–1973) | |
| Seymour, Jim | E | 19 | 3 (1949–1951) | |
| Shabazz, Siddeeq | LB | 2 | 1 (2010) | EDM, WPG |
| Shantz, Bert | T | 0 | 1 (1945) | |
| Sharun, Corbin | LB | 2 | 1 (2015) | EDM |
| Shaver, Luke | DB | 1 | 1 (2001) | WPG |
| Shaw, Dan | DT | 2 | 1 (1977) | |
| Shaw, Dave | C | 8 | 1 (1961) | SSK |
| Shaw, Gerry | E, WR | 154 | 10 (1965–1974) | |
| Shaw, Rick | DB | 31 | 2 (1968–1969) | HAM, WPG |
| Shaw, Bob | E, K | 32 | 3 (1951–1953) | TOR |
| Shell, Lin-J | CB, LB | 18 | 1 (2014) | BC, TOR, WPG |
| Shepherd, Jacoby | DB | 2 | 1 (2005) | |
| Sherbina, Lorne | DT | 64 | 4 (1974–1977) | |
| Sherman, Tom | QB | 7 | 1 (1976) | |
| Sherman, Will | E | 16 | 1 (1953) | |
| Sides, Jim | FB | 3 | 1 (1956) | |
| Silye, Jim | DB, HB | 87 | 6 (1969–1971, 1973–1975) | |
| Simien, Kevin | WR | 0 | 1 (1991) | WPG |
| Simmerling, Christian | DB | 8 | 1 (2004) | |
| Simmons, Jasper | LB | 4 | 1 (2015) | OTT, TOR, WPG |
| Simmons, Ramsey | DE | 1 | 1 (1976) | |
| Simms, Eddie | HB | 11 | 1 (1956) | SSK, TOR |
| Simonton, Ken | RB | 1 | 2 (2007–2008) | |
| Simpson, Hugh | FB | 12 | 2 (1958–1959) | MTL |
| Simpson, Jacki | E, G | 2 | 1 (1961) | MTL, TOR, WPG |
| Simpson, Juwan | LB | 115 | 8 (2008–2015) | |
| Sims, Freddie | RB | 1 | 1 (1986) | BC |
| Sindani, Richard | WR | 18 | 1 (2018) | |
| Singer, Mark | LB | 38 | 3 (1990–1992) | |
| Singer, Rudy | G | 16 | 3 (1947–1949) | |
| Singh, Bobby | OL | 52 | 3 (2002–2003, 2007) | BC, WPG |
| Singleton, Alex | LB | 54 | 3 (2016–2018) | |
| Sinopoli, Brad | QB, SB, WR | 54 | 4 (2011–2014) | OTT |
| Siroishka, Mike | WR | 4 | 1 (1988) | TOR |
| Skinner, Len | G, T | 16 | 2 (1959–1960) | |
| Skopelianos, Chris | RB | 2 | 1 (1976) | HAM, MTL |
| Slaughter, Nathan | R | 2 | 1 (2015) | |
| Sluman, Ken | E | 15 | 2 (1946–1947) | EDM |
| Small, George | DT | 22 | 3 (1981–1983) | |
| Smith, Brandon | DB, DHB | 158 | 11 (2008–2018) | |
| Smith, Brock | WR | 26 | 2 (1989–1990) | OTT |
| Smith, Clifton | RB | 2 | 1 (2013) | |
| Smith, Damon | DB | 1 | 1 (1994) | |
| Smith, Darrell | RB | 18 | 2 (1982–1983) | WPG |
| Smith, Darryl | DB | 9 | 1 (1982) | OTT |
| Smith, Demetrius “Pee Wee” | WR | 90 | 6 (1990–1995) | |
| Smith, Dorian | DL | 3 | 1 (2012) | WPG |
| Smith, Frank | G | 16 | 1 (1953) | BC, EDM, WPG |
| Smith, Garrett | DL | 21 | 2 (2003–2004) | |
| Smith, Henry | LB | 6 | 1 (1990) | |
| Smith, Akili | QB | 14 | 1 (2007) | |
| Smith, Keith | QB | 5 | 1 (2003) | SSK |
| Smith, Quinn | DL, DT, OL | 40 | 4 (2014–2017) | |
| Smith, Rob | G | 49 | 3 (1986–1988) | BC, MTL, OTT, TOR |
| Smith, Ward | HB | 5 | 1 (1969) | BC, MTL, TOR, WPG |
| Snowden, Herb | FW | 0 | 1 (1945) | CGYB |
| Southern, Jerame | DL | 5 | 1 (2005) | |
| Souza, Michael | QB | 18 | 1 (2004) | |
| Sovio, Henry | TE | 22 | 2 (1975–1976) | BC, EDM |
| Spaith, Keith | K, P, QB | 93 | 7 (1948–1954) | |
| Sparks, Len | DB | 20 | 2 (1966–1967) | BC, OTT, TOR |
| Sparks, Robert | DB | 23 | 2 (1979–1980) | OTT, SSK |
| Sparrow, Bert | U | 1 | 1 (1946) | |
| Spear, Craig | WR | 1 | 1 (2004) | |
| Spencer, Walter | DB | 16 | 1 (2006) | MTL, SSK, TOR |
| Spitzer, Mike | G | 8 | 1 (1968) | |
| Spivey, Lee | OL, T | 11 | 2 (1987–1988) | |
| Spoletini, Tom | G, RB, T | 96 | 6 (1985–1990) | |
| Spoletini, Tony | RB | 48 | 3 (1989–1991) | EDM |
| Spruill, Lafayette “Skippy” | DE | 1 | 1 (1967) | TOR |
| Stafford, Kenny | WR | 4 | 1 (2013) | EDM, MTL |
| Stallings, Tony | RB | 3 | 1 (2005) | |
| Standen, Bob | T | 9 | 1 (1949) | |
| Stanzi, Ricky | QB | 19 | 2 (2017–2018) | |
| Starks, Howard | DB, HB | 116 | 8 (1966, 1969–1975) | MTL |
| Steer, Gil | C | 28 | 2 (1951–1952) | BC |
| Stephens, Wally | HB | 7 | 1 (1947) | |
| Stephenson, Don | C, E, G | 34 | 3 (1963–1965) | EDM |
| Stevenson, Bill | QB | 39 | 3 (1955–1957) | |
| Stewart, Anwar | DE | 5 | 2 (2001, 2012) | MTL |
| Stewart, Brandon | DB | 2 | 2 (2007–2008) | BC, HAM, MTL, WPG |
| Stewart, Gord | DE | 10 | 1 (1974) | HAM, SSK, WPG |
| Stewart, Ron | HB | 1 | 1 (1957) | BC |
| Stewart, Ron | DB, P, QB | 46 | 3 (1967–1968, 1970) | |
| Stewart, Tony | RB | 41 | 3 (1993–1995) | HAM |
| Stocks, Arnie | HB | 9 | 1 (1951) | TOR |
| Stone, Daren | DB | 8 | 1 (2011) | SSK |
| Stone, Don | HB | 29 | 3 (1959–1961) | |
| Storme, Todd | G, T | 19 | 2 (1992–1993) | BC, EDM, OTT, SSK |
| Stoudermire, Troy | DB | 9 | 1 (2018) | EDM, WPG |
| Stover, Michael | DL | 1 | 1 (2012) | |
| St. Pierre, Tim | FB, LB, LS, RB | 52 | 5 (2011–2015) | EDM |
| Strode, Woody | E | 38 | 3 (1948–1950) | |
| Strong, Brian | OL | 6 | 2 (1984–1985) | HAM |
| Sturm, Jerry | C, T | 21 | 2 (1959–1960) | |
| Suderman, Dick | DE, E | 112 | 8 (1964–1968, 1970–1972) | EDM |
| Sullivan, Murray | U | 2 | 1 (1952) | TOR |
| Summers, Demetris | RB | 18 | 2 (2008–2009) | |
| Sumner, Terry | HB | 11 | 1 (1952) | SSK |
| Sutton, Don | T | 4 | 1 (1977) | |
| Sutton, Eric | DB | 18 | 2 (1999–2000) | SSK |
| Sweder, Herb | G | 10 | 1 (1949) | |
| Sweeney, Joe | HB | 5 | 1 (1946) | |
| Sweeney, Leo | C, G | 12 | 1 (1953) | BC |
| Swiston, Paul | OL | 4 | 1 (2015) | WPG |
| Switzer, Veryl | HB | 7 | 1 (1958) | MTL |
| Sykes, James | RB | 77 | 6 (1978–1983) | WPG |
| Syptak, John | DL | 5 | 1 (2007) | |
| “S” player count: 134 | ||||